There's literally nothing wrong with race-mixing or being race-mixed

Tell me the supposedly "reasons" of why is it wrong Sup Forums

Other urls found in this thread:

youtube.com/watch?v=tJ6U4gr4hsw
ncbi.nlm.nih.gov/pmc/articles/PMC1448064/
eurekalert.org/pub_releases/2008-08/uoc--baa081108.php
msu.edu/~renn/RHE-_mixed_race.pdf
nature.com/scitable/topicpage/haldane-s-rule-the-heterogametic-sex-1144
jstor.org/pss/1537084
jstor.org/discover/10.2307/3671304?uid=3739600&uid=2&uid=4&uid=3739256&sid=47699085472247
nytimes.com/1995/02/28/science/orangutan-hybrid-bred-to-save-species-now-seen-as-pollutant.html?pagewanted=all&src=pm
sciencedaily.com/releases/2007/04/070420104723.htm
birdaz.com/blog/2011/02/24/mallards-the-weird-and-the-wonderful/
ncbi.nlm.nih.gov/pubmed/451603
ncbi.nlm.nih.gov/pubmed/1060807
aob.oxfordjournals.org/content/74/2/111.full.pdf
genomebiology.com/content/10/12/r141
t1nyurl.com/6tr9e6t
amazon.com/Race-John-R-Baker/dp/0936396040
ncbi.nlm.nih.gov/pubmed/16282974
jstor.org/stable/4145377
sciencedirect.com/science/article/pii/019188699190057I
sciencemag.org/content/319/5864/813.abstract
psyc.nott.ac.uk/research/vision/jwp/papers/pentonvoak1999.pdf
mbe.oxfordjournals.org/content/14/7/707.full.pdf]
eebweb.arizona.edu/Courses/Ecol406R_506R/Garcia-Moreno1996-Wolf.pdf]
cs.brown.edu/courses/cs143/2009/lecture13.pdf]
beheco.oxfordjournals.org/content/15/5/864.abstract
nature.com/hdy/journal/v83/n2/full/6885550a.html
majorityrights.com/images/uploads/spanish.indian.pdf
guardian.co.uk/technology/2011/jan/30/bright-ideas-oxytocin-hormone-racism
pnas.org/content/early/2011/01/06/1015316108
cdnresearch.net/pubs/private/racebias.pdf
m.phys.org/_news162659550.html
nytimes.com/1996/04/18/sports/baseball-rod-carew-s-daughter-dies.html
time.com/time/health/article/0,8599,1993074,00.html
articles.washingtonpost.com/2013-08-05/national/41085742_1_stem-jeffrey-chell-ancestors
jnci.oxfordjournals.org/content/98/18/1270.full
online.wsj.com/article/SB116096445875393515.html?mg=com-wsj
en.wikipedia.org/wiki/Sickle_cell_anemia
annualreviews.org/doi/abs/10.1146/annurev.ecolsys.27.1.83
ncbi.nlm.nih.gov/pmc/articles/PMC1213928/pdf/163.pdf
plosone.org/article/info:doi/10.1371/journal.pone.0007130
twitter.com/NSFWRedditImage

Ugly children

You're right! London is now a paradise with all the brown dumb people and shit! Fuck I love modern England :D!!!!

You might not look like a clone of your relatives.

leaf hiding behind a meme flag

niggers

Race mixing is alright, it is retarded to judge people by their skin, but it must be prevented in order to preserve your heritage.

Niggers are trash. There's no such thing a half nigger. Those children are niggers and their mother is a whore.

>Auscuck intellectuals

...

>edgy kid

enjoy your migrants

FPBP

Children aren't the same race as you, will struggle with identity their whole lives, will have lower IQ than you, and will like breed with other niggers.

It's a genetic dead end

Yes, if you want to live in a world without pure blonde people.

if anything, we are more of a right-wing nation than you, we don't accept reffos and we are still voting to legalise gay marriage.

I'm mixed. If it wasn't for my grandfather banging a medicine nigger I'd be 100% Aryan. Now I'm too white for pow wows and too dark for Nazi LARPing. I hate it. I'd rather be 100% of one race. I'm at best a diluted German and at worst an improved indian. Feels bad man.

It's not "wrong", it's just better to not do it.

Just like with any other animals we selectively breed. It's not wrong for a valuable dog to breed with a shitty street mutt, it's just you get an offspring without any value from it when you could've gotten another litter of valuable pups.

She "looks christian" interestingly enough.

because white kids will cal them nigger and niggers will call them spics.

you are literally ruining your kids' mental well being by choosing to make them with people outside your in-group

not to mention the fact that mixed kids can't receive organs or marrow transplants

Fuck up commie lysenkoist nigger. Get a fucking high school biology text book and look up what mendalian inheritance is. Breeding between differentiated populations of the same species leads to outbreeding depression.

RACEMIX SHILL THREAD

SAGE

youtube.com/watch?v=tJ6U4gr4hsw

Nah man, it's just that you have a weak ass mindset, that's what is killing you. I'd suggest you move to brazil or the caribbeans and stop complaing about fiting in.

Hmmm... so far the reasons you are giving me of why is it wrong are all dumb stuff like: "RACE-MIXED PEOPLE ARE UGLY" "THEY WON'T FIND AN IDENTITY" "THE CHILDREN WON'T LOOK LIKE YOU" "THEY'LL HAVE LOW IQ" "YOUR HERITAGE WILL DIE"; you know, things that have no scientific basis whatsovere and onlyretarded racists would believe. You know, can you ACTUALLY give me GOOD reasons with evidence? Thanks.

Race mixing helps national integration by helping to form human bonds between races.

some are ugly some are not. just like with any other group. it's stupid responses like this that turn people away from a proper discussion. it's not about being ugly or not ugly its about preserving ones ethnic group, which is not a sin

theres nothing inherently wrong with racemixing and on a small scale it is fine. but if a nation does too much mixing and you couple this with an aggressive immigration policy then the indigenous people will no longer be the majority. too much multiculturalism and mixing also leads to loss of indigenous culture and tradition. this is inevitable and always happens when a people are replaced by another people.
some folks are ok with this and others are not. it is not unreasonable to not want your ethnic group to be replaced and it is not unreasonable to take steps to prevent this from happening.

throughout history i can think of no instance where drastic change in a nation's ethnic demographics hasn't lead to or come about because of conflict and violence. very few people will be wilfully replaced.

Because we can't have inmates running the prison, senpai.

GOBLINOS!!!

>tfw when no black gf to make caramel babies with

Fucking goblinos!

Ifbyou mix with negro species youre a subhuman.

said no sane white man ever

ugly childrens with no culture/education and the end of civilization

im not white but i dont date outside my race

Hey, you know what, I actually agree with you.

This, G*blinos are subhumans, BLACKS are fine and made by nature, Goblinos are anti nature.

well apes should mate with apes
and humans with humans
we don't want to have human/ape hybrids in our societies

>cherrypicking this hard

BTW, the Polish baby looks very cute in newer photos.

what a shame, first time i see some quality genetics thrown away. usually its shitskin whites nigger-loving

the parants noses seem to have merged into one, much prettier noses than the parants

>hoseface
>quality genetics

...

Stop shitting in the gene pool

These ethnicities were separated by thousands of miles of Ocean or land. The natural order would have kept them separate. They are an abomination.

Meme flags were a mistake. Now every brazilian or turkish monkey can make a shit thread and avoid the banter and ridicule

O say can you see...

>Hey, you know what, I actually agree with you.
How would your immigration policy be?

>Polish
That rat is hideous

This is such a strawman.

Many babies are but now it's not.

Mixed race children (especially black with whites) got higher chance of getting a skin cancer and other abnormalities.
Before "hurr durr you are wrong" it's actually scientifically prove.

...

Yes it is. Ugly little fucker

That's why no one wants to fuck Indian vagene. Cuz it smells like curry

Hope these mystery meat fucks don't ever catch bone cancer and need a donor....

NIGGER
I
G
G
E
R

Nope you're just jealous, Amerifat.

nothing, with the exception that everybody will hate you for your partner choice or skin color.
People are racists, even if they seem to be superficially liberal
That's human nature
You belong to them or to the others, something like dancing with both feet on two different parties doesn't exist in real world.

not that user but if it were up to me i would have very strict immigration from non-european countries. slightly more relaxed immigration from european countries. in cases of refugees/asylum seekers i would always prioritise women and children over young men. and all migrants would be spread across the country and not concentrated in a single region as that only causes ghettos to form. anybody newly arrived who commits a serious crime or repeatedly commits minor crimes will be sent back to their country of origin.
in my opinion the non native population of a country should not exceed 15%.

i will say this though if i was in politics i would try to encourage the people of my nation to be as welcoming and accepting of migrants and ethnic minorities as possible. i am completely against genuine forms of racism when they do happen. but i also understand that irresponsible migration policies and a inability to punish migrants and ethnic minorities when they commit crimes due to not wanting to appear racist is a big problem and inevitably leads to racial tension. this is why it is so important to get migration right. the way our politicians are doing it at the moment is just retarded and i think it will lead to conflict in the long run if things dont change

black+white = black body ( lighter skin )
black+asian = asian body ( darker skin )
white+asian = asian body ( lighter/darker skin )

Only asians remain in the end

...

What is it with coal burning whores looking the part?

Shut up nigger

You rob them of any identity. As a result they get a host of mental issues. They also have weaker immune systems, much less compatibility with organs and marrow transplants. Generally ugly as well. If you are white, mixing with any other race is a downgrade, they will essentially be guaranteed to be mediocre cofee colored masses, undifferentiated from the billions of others.

It seems cruel to do that to your children. But I guess most of you degenerates don't think that far ahead and just want to nut in a brown girl

i am hitler reincarnated as a half-jew

>Tell me the supposedly "reasons" of why is it wrong Sup Forums


For a non-black to mate with a black is no different from a non-black mating with an animal.

Blacks are not part of the homo sapien sapien family.

Only good post in this whole thread

i've never really understood ethno-nationalism. like if you actually had even a basic understanding of how biology works, you'd know homogeneity is a terrible idea.

read a book, nazis

The good news is your little island is soon to be a multicultural paradise filled to the brim with all types of great ethnic diversity. Enjoy.

...

Besides the mexicans, i cant really see a "loss of culture" in the usa from racemixing. Most Blacks, Whites, and asians here celebrate and participate in the same holidays, sports, and even hobbies. In a future where everbody is mostly mixed with something, it wouldnt be much different. Again, unless the mexicans start forcing shit like in southern california. its pretty much mexico 2.0 down here.

Genetical similiarity leads to higher in-group cooperation potential and higher chances of survival.

It's been that way, is, and will always be. That is, until white designer babies are mainstream.

>Genetical similiarity leads to higher in-group cooperation potential and higher chances of survival.
Thus your enemy wants you to diversify and undermine your true potential.

>island

do you really not know what an island is?

>racemixing
disgusting
>being race mixed
well what can you do about that. parents made some decisions. best just to be proud of whatever race you are.

>genetical

sounds real scientifical, must be true

Get ready faggot. Your love for diversity and the destruction of your own national identity is destroying you one truck of peace and suicide bomber at a time.

you create dynamics that will affect your extended family, generally for the worse.
>well uh can't we all just get along
ideally it would work this way, but it never does... there's some cultural differences and the troublemakers and either side of the family become exposed to the other side
>aunts, uncles, cousins all have to adapt and change their behavior and even if it's slight it makes a difference
>same thing if a white person/child is introduced into a black/Mexican family so it's not a racist issue
so when these couples get together that feeling they get that they know it will be difficult but love finds a way and all that bullshit is not coming from societal stigma but deep down they know they are literally destroying their family line. I'm not saying it's bad it's just gonna make things harder and not just for you and your family but everyone on both sides of the family...now if you're both rich you can bypass alot of this but that's just usually not the case. but hey it won't matter when we live in a super mixed intergalactic society. so thanks for your hardships.

There is a guy at my work who is half black half white, and he's a total misfit. The black people don't want anything to do with him, and the white people think he's a full blooded nigger.

You sound like a next level Jew? Are you Jewish, non-white, or a self hating white? You are clearly anti-white identity but I am sure you would not think twice about anyone being proud of their black, Islamic, or non-white identity.

The West needs to diversify, even countries like Czech Republic and Denmark. The rest of the world is diversifying racially, not fair for other countries not to do so.

America and other countries should lead a sanction based pressure on the countries refusing to mix racially.

The AIDS run deep with the leaf.

>Nothing wrong with race-mixing
Disagree
>or being race-mixed
Agree

There was no choice in the latter, thus by a race-mixed individual's actions they have done no wrong by simply existing.

Triggered you ey?

The middle East is very diversified genetically with lots of African genes. China will experience diversity soon. India is the result of race mixing.

It's time for the homogenous Western countries to open their borders and accept a certain quota. Maybe they should be pressured to reach about 33% of citizens to be of a non-European background by the next 25 years.

The whole world is diversifying, why should some European countries be left untouched?

i can't believe you don't know what an island is

...

>The middle East is very diversified genetically with lots of African genes
>Citing the Middle East as a model example of diversity
HAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAv

HAHAHAHHAHAHAHAHHAHAHAHAHHAHAHAHAHAHHAHAHAHAHAHHAHAHAHAHAHAHHAHAHAHAHHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHAHAHAHAHHAHAHAHAHHAHAHAHA

Here is your reasons. Pure science.

Mixedrace children suffer from more health problems
ncbi.nlm.nih.gov/pmc/articles/PMC1448064/

Racemixing leads to outbreeding depression & pairings of non-complementary traits.

A massively well-funded study of over 100,000 schoolchildren found that “Adolescents who identify themselves as mixed race are at higher health and behavior risk than those of 1 race.” Indeed, even when controlling for education, socioeconomic status, and other factors, there is an across-the board higher rate of health risks amongst mixed race adolescents than mono-racial adolescents.
ncbi.nlm.nih.gov/pmc/articles/PMC1448064/

One study found that White-Asian mixes had a 2x higher rate of being “diagnosed with a psychological disorder, such as anxiety, depression or substance abuse.”
eurekalert.org/pub_releases/2008-08/uoc--baa081108.php

A study on Black-White mixes in agreement found that ”When it comes to engaging in risky/anti-social adolescent behavior, however, mixed race adolescents are stark outliers compared to both blacks and whites.” This holds true despite being raised in similar environments to mono-racial children.
msu.edu/~renn/RHE-_mixed_race.pdf

Often race-deniers and cultural Marxists will bring up Haldane’s rule, arguing that since races can mix and create fertile offspring, the genetic distance is not too great. Haldane’s rule is “when in the offspring of two different animal races one sex is absent, rare, or sterile, that sex is the heterogametic [XY] sex.”
nature.com/scitable/topicpage/haldane-s-rule-the-heterogametic-sex-1144

Indeed, although Black-White mixes are not sterile and males are not absent, males (the heterogametic sex) are more rare than females.
jstor.org/pss/1537084

he argument regarding Haldane’s rule is also meaningless because different species in the animal kingdom can breed and still produce fertile offspring. The wolf (Canis lupus) and the dog (Canis lupus familiaris), the coyote (Canis latrans), and the common jackal (Canis aureus) are separate species yet can all interbreed and produce fertile offspring.
jstor.org/discover/10.2307/3671304?uid=3739600&uid=2&uid=4&uid=3739256&sid=47699085472247

Two species of orangutan (Pongo abellii from Sumatra and Pongo pygmaeus from Borneo) can interbreed despite having different chromosomal numbers.
nytimes.com/1995/02/28/science/orangutan-hybrid-bred-to-save-species-now-seen-as-pollutant.html?pagewanted=all&src=pm

The common chimpanzee (Pan troglodytes) and the bonobo (Pan paniscus) and many species of birds, such as the pintail (Anas acuta) and the mallard (Anas platyrhynchos), can interbreed as well.
sciencedaily.com/releases/2007/04/070420104723.htm
birdaz.com/blog/2011/02/24/mallards-the-weird-and-the-wonderful/

The gibbon and the siamang can also interbreed to produce a hybrid
ncbi.nlm.nih.gov/pubmed/451603
ncbi.nlm.nih.gov/pubmed/1060807

Some species that aren’t even in the same genus can interbreed.
aob.oxfordjournals.org/content/74/2/111.full.pdf

Black Americans are a hybrid race of around 22% White ancestry
genomebiology.com/content/10/12/r141


This 22% ancestry is the cause of multiple negative health effects due to genetic incompatibility. Indeed, consistent with Haldane’s rule, unmixed Blacks from Africa and White Americans do not have the same rate of birth problems that hybrid American Blacks have: “In 2005, the mortality rate for black infants was 4.4 times higher than that of white infants… African women who come to the United States and have babies experience the same low rate of infant deaths as white American mothers.”
t1nyurl.com/6tr9e6t (docs.google)

Protip: Never feed niggers!!!

“Indiscriminate interbreeding between distinct forms, whether ‘species’ or markedly different races, is not generally beneficial. The defect may show in a change in the sex-ratio of the offspring, probably caused by the early abortion of members of one sex, generally the male in the case of mammals.”
amazon.com/Race-John-R-Baker/dp/0936396040

LTA4H, or “leukotriene A4 hydrolase” is found on chromosome 17. An allele of this gene increases the risk of heart attack (the #1 cause of death in America) in Blacks by more than 250%, but only 16% in Whites. The 30% of Whites with this allele have counteracting genes, while the 6% of Black Americans who obtained it through race mixing do not.
ncbi.nlm.nih.gov/pubmed/16282974

The average rate of success for mixed race couples is around half that of same race couples, 0.127 compared to 0.213.
jstor.org/stable/4145377

There is evidence that the more similar the two people are, the happier their marriage tends to be.
sciencedirect.com/science/article/pii/019188699190057I

A study in Iceland showed that 3rd cousin marriages are the most fertile and successful. Suggesting that mating within one's ethnic/racial group would be more beneficial than outside of one's ethnic/racial group.
sciencemag.org/content/319/5864/813.abstract


One study showed that people tend to find their own face when morphed into the opposite sex most attractive, even when he/she doesn't know it's his own face, strongly suggesting that people typically prefer those who look like themselves, in other words their own racial/ethnic group.
psyc.nott.ac.uk/research/vision/jwp/papers/pentonvoak1999.pdf

Hybrid vigor (heterosis) does not seem to apply to humans as we are already very heterozygous, at 0.776 [mbe.oxfordjournals.org/content/14/7/707.full.pdf] Compared to dogs for example at 0.401. [eebweb.arizona.edu/Courses/Ecol406R_506R/Garcia-Moreno1996-Wolf.pdf]

Although some argue that race mixing "averages out" traits and since average faces are considered more attractive [cs.brown.edu/courses/cs143/2009/lecture13.pdf] then mixed race offspring are more attractive.

However this is fallacious as it assumes we are designed for perfect symmetry, when in fact the magnitude of asymmetry is the correct measurement and this random component fulctuates, also called "fluctuating asymmetry" - so more honestly a lower level of asymmetry correlates with increased attractiveness, not symmetry.
beheco.oxfordjournals.org/content/15/5/864.abstract

But does increased heterozygosity cause lower asymmetry? A meta analysis of 118 datasets in 14 studies showed a very weak inverse correlation between the two, showing that increased heterozygosity has no beneficial effect on symmetry or asymmetry
nature.com/hdy/journal/v83/n2/full/6885550a.html

One study on the craniofacial morphology in White-Amerindian mixed race individuals found that over half of the 52 shape variables deviated from the mathematical average completely shattering the above argument.
majorityrights.com/images/uploads/spanish.indian.pdf


The neurotransmitter oxytocin "makes people more co-operative, benevolent, loyal, generous and trusting of others. It is involved in the parent-child bond - new mothers and fathers have raised levels of oxytocin. Production also increases when people hug and when they have sex and, recent research suggests, when they receive psychological warmth." However, oxytocin has been alleged to "foster racism."
guardian.co.uk/technology/2011/jan/30/bright-ideas-oxytocin-hormone-racism

The study found that "intergroup bias that fuels prejudice, xenophobia, and intergroup violence… Which maybe modulated by brain oxytocin." This suggests that the instinctual desire to pursue the interests of one's own ethnic group to further ensure the existence of one's people is linked to racial bias, coinciding with the observation that diversity is a weakness, not a strength.
pnas.org/content/early/2011/01/06/1015316108

One study found that during the menstrual cycle when women have a higher likeihood of conception, racial bias is increased, especially when the likeihood of sexual intercourse was increased; "increased conception risk was positively associated with several measures of race bias. This association was particularly strong when perceived vulnerability to sexual coercion was high."

>Although egalitarians suggest that only a racist would consider race when it comes to reproduction and mate choice, this study observed a general, innate tendency to prefer one's own race especially when most likely to be impregnated.
cdnresearch.net/pubs/private/racebias.pdf

Race Is A Social Construct?
The Immune System: How Important Is Race?
>"If Nick Glasgow were white, he would have a nearly 90 percent chance of finding a matching bone marrow donor who could cure his leukemia."


The reason that mixed-heritage patients are so hard to match can be found in the immune system. Different races have developed certain proteins, or markers, that are part of the body's natural defenses. These markers help the immune system determine which cells are foreign and should be rejected.

Are cells racist?
A match between two people who share more genetically in common significantly reduces the risk of the donor and recipient cells attacking each other. (READ: cells from people of two different races will attack and fight each other as though they are a virus)

The more people of different backgrounds who produce offspring = the more types that are harder to match.
Multiracial patients have uncommon profiles and since there can be many possible racial and ethnic combinations in multiracial societies, finding a match can still be extremely difficult.
m.phys.org/_news162659550.html

As an example, a White mother of mixed-race child would have more genetically in common with a random White person on the street than with her own child.
If such a dramatic and fundamental alienation from your own parents if not horrific enough, With a mixed-race child diagnosed with leukaemia, every member of the child's own family becomes an incompatible donor for a bone-marrow transplant, and finding a compatible donor is unlikely:

>One obstacle to finding a matching donor was her mixed ethnic background. Her father is black, with West Indian and Panamanian roots. Her mother is white, with Russian-Jewish roots. In addition, only 5 percent of registered donors are black.
nytimes.com/1996/04/18/sports/baseball-rod-carew-s-daughter-dies.html

Bone Marrow Transplants: When Race Is an Issue
>''Compared to organ transplants, bone marrow donations need to be even more genetically similar to their recipients. Since all the immune system's cells come from bone marrow, a transplant essentially introduces a new immune system to a person. Without genetic similarity between the donor and the patient, the new white blood cells will attack the host body.
time.com/time/health/article/0,8599,1993074,00.html

Race matters when a patient needs a stem cell or marrow transplant
>If you become ill with a blood cancer or other disease that requires a stem cell transplant, here's an uncomfortable fact: Your race matters. Diversity is a strength in much of life, [citation needed!] but it's a curse when finding a stem cell donor match.
articles.washingtonpost.com/2013-08-05/national/41085742_1_stem-jeffrey-chell-ancestors


The Race for Ancestral Genetics in Clinical Trials
>A seasoned cancer researcher would never set up a study in which all the ill patients were, say, Canadian, and all the healthy controls were Japanese. And yet cancer researchers risk making a similar mistake if they overlook genetic information that fleshes out what many of us like to think of as race or ethnicity, some experts say.

>Fortunately, awareness of how ancestral genetics might contribute to risk of disease and drug response in people has risen over the last several years. Studies that look directly at the problem are on the rapid rise, and this increased interest has biotechnology companies lowering the cost of tests that determine genetic ancestry, thanks to a little competition. However, experts have yet to decide on how to genetically define ancestry, suggesting examining anywhere from a handful to hundreds of gene variants.

>Not including information on the race or ethnicity of study volunteers could skew disease risks as stronger or weaker than they really are.

Hee hee ha ha ha

>"Alzheimer's disease is the poster child for this problem," says pharmacogeneticist Esteban Burchard, M.D., of the University of California in San Francisco. A variant of the gene ApoE4 is a strong genetic risk factor for early-onset Alzheimer's disease, and the characteristic most likely to raise or lower that risk is race.

>"It occurs in about 20% of the African American population, and it means nothing. It occurs in about 6% of the Japanese, and it makes their risk six times higher [than that for white people]," Burchard said. "Something about being Japanese unleashes the wrath of the gene, and something about being African American attenuates it."
jnci.oxfordjournals.org/content/98/18/1270.full


BiDil
>The FDA have approved a heart failure drug called Bidil, but only for blacks, as blacks do not benefit from conventional heart failure drugs.
online.wsj.com/article/SB116096445875393515.html?mg=com-wsj

Sickle-Cell Disease
Sickle cell anaemia is a condition found almost exclusively in blacks, about 1 in 4 west Africans carry the gene for it, almost no whites do. Any whites who carry the gene most likely have a black ancestor.

As a result of population growth in African-Caribbean regions of overseas France and immigration from North and sub-Saharan Africa to mainland France, sickle cell disease has become a major health problem in France. SCD has become the most common genetic disease in this country.
en.wikipedia.org/wiki/Sickle_cell_anemia


Invasive species: Genes Are Destroyed With Admixture/Racial Mixing

Extinction by hybridization:
>Nonindigenous species can bring about a form of extinction of native flora and fauna by hybridization and introgression either through purposeful introduction by humans or through habitat modification, bringing previously isolated species into contact. These phenomena can be especially problematic for rare species coming into contact with more abundant ones. Increased use of molecular techniques focuses attention on the extent of this underappreciated problem that is not always apparent from morphological observations alone. Some degree of gene flow is a normal, evolutionarily constructive process, and all constellations of genes and genotypes cannot be preserved. However, hybridization with or without introgression may, nevertheless, threaten a rare species' existence.
annualreviews.org/doi/abs/10.1146/annurev.ecolsys.27.1.83


The Island Model with Stochastic Migration:
>It is supposed that the migration rate and the immigrant gene frequency are independent of each other in each generation, and each of them is independently and identically distributed in every generation. The treatment is confined to a single diallelic locus without mutation. If the diploid population is infinite, selection is absent and the immigrant gene frequency is fixed, then the gene frequency on the island converges to the immigrant frequency, and the logarithm of the absolute value of its deviation from it is asymptotically normally distributed.
The above implies that if you have two genes in some frequency in the immigrant population, under one way migration that frequency becomes the dominant frequency on the island.


>We investigated various cases of the island model with stochastic migration. If the population is infinite, the immigrants have a fixed gene frequency and the alleles are neutral, the gene frequency on the island converges to that of the immigrants.

based nips

Whitest woman in merica 2019

What this means is that the genes initially on the model island, in effect, disappeared.
ncbi.nlm.nih.gov/pmc/articles/PMC1213928/pdf/163.pdf

Evolution with Stochastic Fitness and Stochastic Migration
>Migration between local populations plays an important role in evolution - influencing local adaptation, speciation, extinction, and the maintenance of genetic variation.

>A number of studies have shown that when per capita population growth rate is treated as a random variable, rather than a fixed parameter, then directional evolution is influenced not only by the expected fitness of each phenotype, but also by the variance and other moments [23], [28]-[33]. This follows from the fact that, in a closed population, change in mean phenotype is inversely proportional to mean population fitness
plosone.org/article/info:doi/10.1371/journal.pone.0007130


Figure 1. The consequences of a negative correlation between fitness and immigration rate: