Loneliness from a female perspective

After watching a few miserable movies about loners I was wondering where or what are the miserable movies with equally socially retarded female leads? I have almost zero idea what it's like for a female autist.

Don't give me nothing too miserable straight away, save that for last.

Misery

Castaway On The Moon

kieslowskis three colors

Ghost World a little bit

Gray Gardens.

Kill bill

A Bride for Rip Van Winkle

Also one of the best films of last year. If not the best.

Ghost World and Slums of Beverly Hills come to mind.

Wat.