>Did Civil War 2 kill his career?
That's hard to say. I'd say the problems started earlier.
>33 Spider-Men II #2 41,765
Well the previous series was like this:
06/12 Spider-Men #1 of 5 - 94,548
06/12 Spider-Men #2 of 5 - 68,283 (-27.8%)
07/12 Spider-Men #3 of 5 - 57,739 (-15.4%)
08/12 Spider-Men #4 of 5 - 54,215 ( -6.1%)
09/12 Spider-Men #5 of 5 - 52,525 ( -3.1%)
If it stays at 40,000 to lower 30,000's then it's a slight decline from the first series but if it goes like 30,000 or below then there's a problem. This would've been better had they placed it right after Secret Wars to explain Miles' situation to keep the momentum going.
>72 Spider-Man #19 30,387
Miles' comic was already doing those numbers by the ninth issue of the previous series. Then again that may be because people were also losing interest in the Ultimate universe at an accelerated rate (and at the same time, Bendis' Spider-Man was the highest selling of the Ultimate titles at that point)
>70 Defenders #4 31,120
>100 Jessica Jones #11 22,774
This is not that far off from his Spider-Woman sales from seven years ago. But then again Spider-Woman didn't have a Netflix show back then either. And Spider-Woman's cover price was lower, so I guess Jessica Jones doing these numbers is okay-ish? I forgot what sales on Alias and The Pulse were.
Defenders I'm not sure how to judge because it's usually a lower selling book but at the same time it's got a Netflix show.
>80 Invincible Iron Man #10 27,675
>91 Infamous Iron Man #11 24,676
These are really bad especially when you remember they were pushing Bendis' Iron Man to be the flagship of ANAD like said. Infamous is basically back to being around the sales level of International Iron Man and Invincible is around the sales level of International, which is a really bad thing considering the book was in the 40,000's before.